| Rank | Name | Year | School | Meet | Time |
| 1 | Libby Dowty | 2024 | Indian Creek | Franklin Inv. | 17:35.1 |
| 2 | Malyka Abramson | 2013 | Avon | Franklin Inv. | 17:56.5 |
| 3 | Mackenzie Caldwell | 2013 | Columbus North | Franklin Inv. | 18:08 |
| 4 | Brenner Hanna | 2020 | Greensburg | Regional | 18:20 |
| 5 | Allie Dalton | 2015 | Greenwood Christian | Franklin Inv. | 18:21 |
| 6 | Lauren Klem | 2020 | Franklin | Johnson Co. | 18:25 |
| Laura Barco | 2025 | Martinsville | Franklin Inv. | 18:25.2 |
| 8 | Lillian Rollings | 2025 | Greenwood | Franklin Inv. | 18:29.3 |
| 9 | Erin Sullivan | 2016 | Southport | Sectional | 18:33 |
| 10 | Lily Rollins | 2024 | Greenwood Comm | Franklin Inv. | 18:42.6 |
| 11 | Chanli Mundy | 2011 | Terre Haute North | Franklin Inv. | 18:43 |
| 12 | Abby Fleetwood | 2022 | Indian Creek | Sectional | 18:43.6 |
| 13 | Tori Schoettmer | 2012 | Center Grove | Johnson Co. | 18:47 |
| 14 | Lily Myers | 2022 | Bloomington South | Franklin Inv. | 18:48.97 |
| 15 | Kieran Casey | 2012 | Perry Meridian | Franklin Inv. | 18:49 |
| 16 | Samantha Woodford | 2014 | Plainfield | Mid-State Conf. | 18:49 |
| 17 | Tori Jackson | 2023 | Whiteland | Johnson Co. | 18:50.3 |
| 18 | Rachael Sollman | 2011 | Columbus North | Franklin Inv. | 18:55 |
| 19 | Carys Glen Jones | 2024 | Columbus North | Franklin Inv. | 18:56.7 |
| 20 | Jordan Timmons | 2012 | Center Grove | Johnson Co. | 18:57 |
| Rank | Name | Year | School | Meet | Time |
| 1 | Luke Brahm | 2011 | Ben Davis | Franklin Inv. | 15:27.82 |
| 2 | Will Jefferson | 2020 | Whiteland | Mid-State Conf. | 15:29.53 |
| 3 | Ty Garrett | 2022 | Center Grove | Sectional | 15:30.7 |
| 4 | Andrew Diehn | 2011 | Columbus North | Franklin Inv. | 15:33 |
| 5 | Tyeson Mundy | 2011 | Terre Haute North | Franklin Inv. | 15:34 |
| Joseph Day | 2025 | Columbus North | Franklin Inv. | 15:34.9 |
| 7 | Zack Snider | 2013 | Brebeuf | Franklin Inv. | 15:35 |
| 8 | David Dalton | 2013 | Greenwood | Franklin Inv. | 15:37 |
| 9 | Nathan Burns | 2022 | Mooresville | Sectional | 15:42.7 |
| 10 | Jace Lowry | 2010 | Martinsville | Mid-State Conf. | 15:43 |
| 11 | Parker Mimbela | 2022 | Center Grove | Sectional | 15:45.9 |
| 12 | Joe Hawkins | 2025 | Greensburg | Franklin Inv. | 15:46.0 |
| 13 | Ryan Rheam | 2022 | Bloomington South | Franklin Inv. | 15:48.42 |
| 14 | Clayton Bowie | 2013 | Southport | Sectional | 15:49 |
| 15 | Michael Passmore | 2012 | Mooresville | Franklin Inv. | 15:50 |
| Neal White | 2024 | Columbus North | Franklin Inv. | 15.50.0 |
| 17 | Isaiah White | 2013 | Perry Meridian | Franklin Inv. | 15:52 |
| 18 | Dalton Kane | 2018 | Plainfield | Mid-State Conf. | 15:53 |
| 19 | Michael Sublette | 2011 | Columbus North | Franklin Inv. | 15:54 |
| 20 | Griffin Miller | 2014 | Center Grove | Sectional | 15:54 |